CIRM Centers of Excellence
The Stem Cell Center is a cornerstone program of campus biomedical research that capitalizes on our strengths in basic and preclinical research, as well as collaborations with neighboring research institutions, to support high impact investigations with several major emphases: (1) stem cell self-renewal, (2) hematopoietic differentiation, (3) neural differentiation and neurodegeneration, (4) cardiovascular and skeletal muscle differentiation, and (5) cancer and cancer stem cells. The proposed CIRM Center of Excellence (CoE) will be the focal point for these efforts and will be critical to our ability to expand this program of world class basic and preclinical stem cell research.
The CoE will assemble a critical mass of investigators who will promote interdisciplinary collaborations among campus biologists, engineers, and physical scientists to make important discoveries that lay the foundation for developing new therapies for human disease. Basic investigations of genes that control stem cell self-renewal and pluripotency will aid the engineering of synthetic microenvironments for the large scale, safe expansion of human embryonic and other stem cells for cell replacement therapies and diagnostic applications. Likewise, elucidation of fundamental mechanisms of neurodegenerative disease will lead to new regenerative medicine therapies for Alzheimer
University of California, Berkeley